What are the advantages/disadvantages of the different exported folder structures.

What are the advantages/disadvantages of the different exported folder structures.

What are the reasons I would want to use a Flat Hierarchy? Is there an advantage to that format? Are there in inherent advantages/disadvantages to any of the other types of folder structure? I am leaning toward the Year/Month/date but with ~3TB of data I do not want to make a mistake.